Works very well. I only needed this to hold on the Mepore bandages after carpal tunnel surgery. So on the palm of the hand it is tricky to have a non irritating bandage actually stick to the skin. This one was a fraction of the price compared to some other brands. I was very happy to find a more inexpensive option. I don’t know if it would work for appliances such as ostomy supplies, but for palm of the hand? Bandage did not budge until I pulled off a couple days later.